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KMID : 1172020000010010099
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Journal of Korean Bioethics Association
2000 Volume.1 No. 1 p.99 ~ p.122
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Research Ethics and Policy Involving Vulnerable Subjects and Human Body Components
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Park Eun-Jung
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Abstract
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This article consists of two parts. The first part of this article discusses research ethics and policy involving human subjects, vulnerable subjects in particular, such as children, mentally infirm adults, and prisoners. In the second part, this article deals with research ethics and policy of human body components, i. e., research on fetuses in utero, research using fetal tissue, and research on preimplantation zygotes. As for research involving the vulnerable, it is important to balance out two competing demands: the need for special protection from abuse and exploitation on the one hand and the
social need for research on the vulnerable on the other. Topics discussed in this part of the article include incompetence for special protection, the assent of the pediatric subject, imposing risks on vulnerable subjects, and choice of surrogate decision maker, protecting the institutionalized subjects etc. In the second half of the article, the author presents a number of different sets of policies, varying from one country to another, on reproductive and fetal research. They represent an
attempt to regulate the research contemporaneous with the actual development of the research. And this implies that the official policies on this area of research are in fact compromise-based ones.
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KEYWORD
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research involving children, research involving mentally infirm adults, research involving prisoners, research on fetuses in utero, research using fetal tissue, research on preimplantation zygotes
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